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Very high concentrations of the drug develop within the skin, so it is effective in treating superficial fungal infections. Ketoconazole can be used in the treatment of androgenetic alopecia. The head or for more extent areas on the chest or in the face. It is given with food. The wonder ingredient Ketoconazole, a synthetic anti-fungal drug. The main concern with Ketoconazole is the risk of liver problems, usually after it has been taken for prolonged periods.