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Propranolol is a competitive antagonist which specifically competes with beta-adrenergic receptor stimulating agents for available beta-receptor sites. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction. Propranolol from Inderal tablets is rapidly and completely absorbed from the gastrointestinal tract and undergoes extensive presystemic elimination due to its high hepatic clearance. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and systolic ejection period. If adrenaline is given with Propranolol, laboratory determinations should be made at regular intervals.
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