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If you have ischemic heart disease. When Propranolol is combined with another antihypertensive drug, which is a type of medicine called a beta-blocker. Propranolol should be administered with caution since it may block bronchodilation produced by endogenous and exogenous catecholamine stimulation of beta-adrenergic receptors. Care should be taken if adrenaline is given with Propranolol, as this combination can cause severely high blood pressure and slow heart rate, tremor and nausea.

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