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Misoprostol can be absorbed through both the vaginal mucosa and the buccal mucosa. The buccal mucosa. Misoprostol can be absorbed through both the vaginal mucosa and the buccal mucosa. Cytotec is best taken with or after meals and at bedtime to minimize diarrhea, or as directed by your doctor. Cytotec helps the stomach protect itself against acid damage. Before taking Misoprostol, tell your doctor or pharmacist if you are allergic to it. Cytotec brings on extremely strong, intensive contractions, which is where stomach ulcers occur. This medicine may cause some unwanted effects.
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