Beta-blockers. Several reports in the published literature describe cases in which Propranolol was used as a suicide agent. Propranolol is used to prevent migraine, although it is not fully understood how Propranolol works in this area. Propranolol should be administered with caution since it may block bronchodilation produced by endogenous and exogenous catecholamine stimulation of beta-adrenergic receptors. Propranolol exerts ant arrhythmic effects in concentrations producing beta-adrenergic blockade, which appears to be its principal ant arrhythmic mechanism of action. The heart's need for oxygen, which means it can also be used in the management of angina. Propranolol can, in certain patients, be used alone or as an initial agent in patients in whom, in the judgment of the physician, treatment should be started with a beta-blocker rather than a diuretic.
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